While a day or two staying awake late into the night, or a couple of days after travelling through a few times zones, may be uncomfortable, repeatably disrupting your circadian clock can have adverse health consequences, as every immune system in your body starts to malfunction.
It makes the immune system so weak that germs and bugs that don’t usually cause any trouble can upset your stomach or even cause flulike symptoms. It has been documented that shift workers experience more than non-shift workers, particularly gastrointestinal diseases, obesity, diabetes, and cardiovascular diseases.
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